For what reason do NSAIDs need to be dispensed with a medication guide?

NSAIDs, or non-steroidal anti-inflammatory drugs, are commonly used medications known for their pain-relieving and anti-inflammatory properties. The need to provide a medication guide with NSAIDs is primarily due to the significant risk of gastrointestinal (GI) bleeding associated with their use.

When NSAIDs are taken, they can interfere with the stomach's ability to protect itself from harsh acids, thereby increasing the likelihood of developing ulcers and experiencing GI bleeding. This risk is particularly important for certain populations, such as older adults or those with a history of gastrointestinal issues, making it critical that patients understand these risks before starting therapy. The medication guide serves to inform patients about the signs and symptoms of potential GI problems, ensuring they are aware of what to look for and the importance of seeking medical attention if necessary.

While NSAIDs carry risks for respiratory issues, renal failure, and cardiovascular problems, the requirement for a medication guide specifically highlights the concern over GI bleeding due to its potentially serious consequences and the frequency with which it occurs in patients taking these medications.